There is a possibility that specific dietary components may increase or decrease cancer risk. While few studies have definitively shown that dietary components may cause or protect against cancer, the following have been studied as possible associations with cancer risk. External links are given for more information, and certain cancer types may find more or less risk for any of the following dietary components.
- ALCOHOL– Although red wine has been suspected of reducing cancer risk, there is no scientific evidence for such an association. Also, alcohol is a known cause of cancer. Heavy or regular alcohol consumption increases the risk of developing cancers of the oral cavity (excluding the lips), pharynx (throat), larynx (voice box), esophagus, liver, breast, colon, and rectum. The risk of developing cancer increases with the amount of alcohol a person drinks. For more information, see the fact sheet on Alcohol and Cancer Risk.
- ANTIOXIDANTS– Antioxidants are chemicals that block the activity of other chemicals, known as free radicals, that may damage cells. Laboratory and animal research has shown that exogenous antioxidants can help prevent the free radical damage associated with the development of cancer, but research in humans has not demonstrated convincingly that taking antioxidant supplements can help reduce the risk of developing or dying from cancer. Some studies have even shown an increased risk of some cancers. For more information, see the Antioxidants and Cancer Prevention fact sheet.
- ARTIFICIAL SWEETENERS– Studies have been conducted on the safety of several artificial sweeteners, including saccharin, aspartame, acesulfame potassium, sucralose, neotame, and cyclamate. There is no clear evidence that the artificial sweeteners available commercially in the United States are associated with cancer risk in humans. For more information, see the Artificial Sweeteners and Cancer fact sheet.
- CALCIUM– Calcium is an essential dietary mineral that can be obtained from food and supplements. Research results overall support a relationship between higher intakes of calcium and reduced risks of colorectal cancer, but the results of studies have not always been consistent. Whether a relationship exists between higher calcium intakes and reduced risks of other cancers, such as breast and ovarian cancer, is unclear. Some research suggests that a high calcium intake may increase the risk of prostate cancer. For more information, see the fact sheet on Calcium and Cancer Prevention.
- CHARRED MEAT– Certain chemicals, called HCAs and PAHs, are formed when muscle meat, including beef, pork, fish, and poultry, is cooked using high-temperature methods. Exposure to high levels of HCAs and PAHs can cause cancer in animals; however, whether such exposure causes cancer in humans is unclear. For more information, see the Chemicals in Meat Cooked at High Temperatures and Cancer Risk fact sheet.
- CRUCIFEROUS VEGETABLES– Cruciferous vegetables contain chemicals known as glucosinolates, which break down into several compounds that are being studied for possible anticancer effects. Some of these compounds have shown anticancer effects in cells and animals, but the results of studies with humans have been less clear. For more information, see the Cruciferous Vegetables and Cancer Prevention fact sheet.
- FLUORIDE– Fluoride in water helps to prevent and can even reverse tooth decay. Many studies, in both humans and animals, have shown no association between fluoridated water and cancer risk. For more information, see the Fluoridated Water fact sheet.
- GARLIC– Some studies have suggested that garlic consumption may reduce the risk of developing several types of cancer, especially cancers of the gastrointestinal tract. However, the evidence is not definitive. For more information, see the Garlic and Cancer Prevention fact sheet.
- TEA– Tea contains polyphenol compounds, particularly catechins, which are antioxidants. Results of epidemiologic studies examining the association between tea consumption and cancer risk have been inconclusive. Few clinical trials of tea consumption and cancer prevention have been conducted and their results have also been inconclusive. For more information, see the fact sheet on Tea and Cancer Prevention.
- VITAMIN D– Vitamin D helps the body use calcium and phosphorus to make strong bones and teeth. It is obtained primarily through exposure of the skin to sunlight, but it can also be obtained from some foods and dietary supplements. Epidemiologic studies in humans have suggested that higher intakes of vitamin D or higher levels of vitamin D in the blood may be associated with a reduced risk of colorectal cancer, but the results of randomized studies have been inconclusive. For more information, see the Vitamin D and Cancer Prevention fact sheet.
The Arthur Lab is specifically interested in the importance of leafy green and cruciferous vegetables for cancer patients and survivors. Click here for more information and recipes.